ACRLAnGes Clinical Research Laboratory

What is AnGes Clinical Research Laboratory?

AnGes Clinical Research Laboratory (ACRL), which opened in April 2021, is an inspection laboratory*1
the main purpose of which is to perform testing for rare genetic diseases.


AnGes's efforts to address intractable and rare diseases

Since its founding, AnGes has been researching and developing drugs for rare and intractable diseases.

Although more rare genetic diseases have become treatable, there are certain diseases for which, even if they are treatable, the desired therapeutic effect can be achieved only when treatment is initiated before symptom onset. Some other diseases have few characteristic symptoms and are difficult to detect with standard diagnostic techniques. It is important that the treatment of rare genetic diseases should be initiated early in the course of disease, preferably before the onset of disease.

For rare genetic diseases, newborn mass screening, which tests all newborns born in Japan for inherited metabolic diseases*2, is currently provided free of charge as a public program, mainly by local governments in each region, leading to early detection and treatment.

For diseases caused by genetic changes that can be detected and treated at an early stage other than those covered by the newborn mass screening program, local governments and organizations in each region offer fee-based additional testing for those who wish to receive it.

Since April 2021, our ACRL has been contracted to provide testing services for optional screening*3, fee-based testing provided by the Clinical & Research Association for Rare, Intractable Diseases (CReARID), for those who wish to receive testing.

In the future, we will also seek to be contracted to provide additional testing services for diseases (rare genetic diseases) not covered by the newborn mass screening, which are being performed by local governments, organizations, and laboratory companies nationwide, thereby contributing to the promotion of awareness and understanding of rare genetic diseases and the dissemination of treatment for such diseases.

  • *1)It is a facility that inspects inspection materials collected or excreted from the human body. This facility is registered based on the Act on Medical Technologist.
  • *2)Inborn errors of metabolism are diseases in which metabolism is impaired due to the natural inability of enzymes and transporters to function properly, and abnormal substances are accumulated in the body or the body lacks necessary substances, resulting in a variety of symptoms.
  • *3)For more information on optional screening, please visit CReARID's website.

Additional testing for rare genetic diseases

Flow of additional testing for rare genetic diseases

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